All posts by Keith

I’m a controversialist and catalyst, quietly enabling others to develop by providing different ideas and views of the world. Born in London in the early 1950s and initially trained as a research chemist I retired as a senior project manager after 35 years in the IT industry. Retirement is about community give-back and finding some equilibrium. Founder and Honorary Secretary of the Anthony Powell Society. Chairman of my GP's patient group.

Monthly Links

This month’s collection of links to items you maybe didn’t want to miss.


Science, Technology, Natural World

Let’s start with one of the hard questions … What is Life? [LONG READ]

New observations from the Gaia telescope have provided the most detailed picture of the Milky Way to date (above).

At the other end of things, there is much we don’t yet know about the ocean depths and what lives there. [LONG READ]

This is amply demonstrated in ever detailed mapping of the depths of the Southern Ocean

… current investigations of, and hunts for, underwater volcanoes [LONG READ] …

… a flourishing hidden world of marine life discovered under the Antarctic ice

… and the mysterious sea creatures which surface at night but spend the day in the depths. [LONG READ] [££££]

Back on dry land researchers have proposed a new story of the origin of the domestic chicken 3500 years ago in rice fields.

And now two items on one of my recurrent themes: wasps …
What would happen if all the wasps disappeared? [VIDEO]
And secondly how not to let wasps spoil your picinic.

On a totally different tack, apparently trees around art galleries provide the art works with significant protection from pollution.

It turns out dandelions are more interesting that most of us knew. As a kid I learnt that the petals could be used to make very agreeable wine, the leaves could be put in salad and are a diuretic, and the roots could be roasted and used as a coffee substitute. What I didn’t know is that dandelions can be used to make rubber.

Finally in this section, scientists have discovered the world’s largest bacterium – and it’s the size of an eyelash.


Health, Medicine

Here’s the inside story of RECOVERY, the largest Covid-19 clinical trial, which transformed treatment. [LONG READ]

It is estimated that at least 1 in 7 people worldwide have contracted Lyme disease. [££££]

More surprising news is that 1 in 500 men carry an extra sex chromosome, being either XXY or XYY rather than the normal XY – and most don’t know.

[TRIGGER WARNING] From the “I thought we already knew this” file, a large study has confirmed that most miscarriages are caused by genetic errors. [££££}

Monkeypox may not mutate very quickly, but it still does mutate and adapt.

After some scientists object, the WHO is proposing to rename Monkeypox, but the placeholder name “hMPXV” (human MonkeyPoX Virus) doesn’t seem to me to be so much better.

There are tiny mites living in our hair follicles, and they have sex on our faces at night. And you thought your cat was a furry pervert!

Which brings us nicely(!?) to …


Sexuality

Yet more thoughts on how us geriatrics can still have great sex.

An interview with Julia Shaw about Bi, her new book on bisexuality.


Environment

A pair of peregrines have hatched three chicks on the roof of (my local) Ealing Hospital, which is slightly bizarre as the hospital no longer has a birthing unit.


Social Sciences, Business, Law

I’m not quite sure where these next two items should really belong, so I decided they’re “business” …

Cargo vessels are getting ever larger, but how can you rescue one when it gets into trouble?.

What do you do with an unwanted supertanker?

Some thoughts on Artificial Intelligence and the patent system from our favourite drug research chemist.


Art, Literature, Language, Music

I’ve defined this as art, because, south of Brussels, Charleroi has a truly surreal metro system. [LONG READ]


History, Archaeology, Anthropology

You’ll remember that 5300-year-old mummified corpse found in the Alps some years ago … well it seems that he’s told us a lot about ancestral diet, compared with modern diet. [LOND READ]

There’s an Iron Age site near Cambridge where archaeologists have found the burial of a huge number of frogs – and they don’t know the reason for the burial.

The remains of over 140 people have been found at an Anglo-Saxon burial site on the route of the HS2 rail line.

Another from the annals of the “thought already known” … researchers say that the Black Death almost certainly started in Central Asia.

Here’s Dr Eleanor Janega (our favourite medievalist) on drag, femininity and sexuality in the before times.

Queen Elizabeth I commissioned the pirate Sir Francis Drake to chart the west coast of the Americas, disrupt the Spanish colonisation, and naturally bring back booty. In the process Drake, in the Golden Hind, became the first Englishman to circumnavigate the world, taking 1017 days.

And from the same era, here’s a stunning piece of French interior: La grande cheminée du manoir de Coëtcandec, exposée au château des Rohan à Pontivy. [It’s in French, but the images are stunning.]
[LONG READ]

A century later HMS Gloucester was wrecked off the Norfolk coast. It was carrying the future James II at the time; and I seem to recall Samuel Pepys was involved somewhere. The wreck has been located and is being investigated.


London

Here we have three items from IanVisits

There are 13 green huts dotted around London; they’re the remaining Cabman’s Shelters (originally there were at least 61). Now another two have been given listed status, making 12 of the remaining 13 protected.

In Pinner churchyard there’s a strange coffin floating in mid-air (well, sort of!).

And here’s Ian’s report of a recent tour of Harrow School.


Food, Drink

It seems that climate change is altering the chemistry of wine, and not always in a good way. [LONG READ]


Lifestyle, Personal Development, Beliefs

Finally an number of items on one of my core beliefs: naturism and nudism …
12 reasons to be a nudist.
On the many benefits of naturism.
No, nudity is not sexual – unless you make it so.
Three reasons why nudity is not better accepted.


June Quiz Answers

OK, so here are the answers to this month’s quiz questions. All should be able to be easily verified online.

June Quiz Questions: Famous Quotations

Who said …

  1. “Any sufficiently advanced technology is indistinguishable from magic.” Arthur C Clarke
  2. “Every harlot was a virgin once.” William Blake
  3. “I have always believed that I was slightly saner than most people. Then again, most insane people think this.” Truman Capote
  4. “For a successful technology, reality must take precedence over public relations, for nature cannot be fooled.” Richard Feynman
  5. “In converting Jews to Christians, you raise the price of pork.” William Shakespeare, The Merchant of Venice

Answers were correct when questions were compiled in late 2021.

Monthly Quotes

Our usual collection of quotes encountered.


Conspiracy is the default explanation of a mystery when you’re looking for meaning. Uncertainty is the default when you’re looking for truth.


[A molecule called Celastrol] does all kinds of stuff in cell assays and animal models … and you can basically find papers that will illustrate it doing anything you feel like seeing – antibacterial, anti-inflammatory, anticancer, antidiabetic, antioxidant, insecticide, you name it. It’s probably a decent floor polish, although I’m not sure I’d recommend its use as a dessert topping.
[Derek Lowe; https://www.science.org/content/blog-post/fun-protein-degradation]


I don’t think that AI is going to provide answers … any time soon – largely because the difficulty is lack of knowledge in the first place. You can’t expect the software to take a bunch of used pizza boxes and find a route to convert them into gold jewellery, and unfortunately a lot of our knowledge (when you look at it on the absolute scale) is at the used pizza box stage.
[Derek Lowe; https://www.science.org/content/blog-post/ai-and-patent-system]


Pessimism of the Intellect, Optimism of the Will
[Antonio Gramsci]


Why is being a nerd bad? Saying I notice you’re a nerd is like saying, “Hey, I notice that you’d rather be intelligent than be stupid, that you’d rather be thoughtful than be vapid, that you believe that there are things that matter more than the arrest record of Linsey Lohan. Why is that?”
[John Green]


In war, the strong make slaves of the weak, and in peace the rich make slaves of the poor.
[Oscar Wilde]


When we exist, death is not; and when death exists, we are not. All sensation and consciousness ends with death and therefore in death there is neither pleasure nor pain. The fear of death arises from the belief that in death, there is awareness.
[Epicurus, died 270BC]


You are not lazy, unmotivated, or stuck. After years of living your life in survival mode you are exhausted. There is a difference.
[Nakeia Homer]


The Brexit agreement was written in English so they could understand it.
[Ursula von de Leyen, EU President]


The good life is one inspired by love and guided by knowledge.
[Bertrand Russell]


It is obvious that we can no more explain a passion to a person who has never experienced it than we can explain light to the blind.
[TS Elliot]


I began to realize how important it was to be an enthusiast in life. He taught me that if you are interested in something, no matter what it is, go at it at full speed ahead. Embrace it with both arms, hug it, love it and above all become passionate about it. Lukewarm is no good. Hot is no good either. White hot and passionate is the only thing to be.
[Roald Dahl, My Uncle Oswald]


The human body is the best work of art.
[Jess C Scott]


Monkeypox 7. Another Quick Update

This is yet another post of a few quick notes from the last couple of weeks.

The headline message remains: The risk is low so don’t be concerned, but do be vigilant.


  1. Cases are appearing with no known contacts with confirmed cases, suggesting transmission is being missed due to undetected circulation of the virus. [1]
  2. Many cases appear non-typical with the rash appearing before other symptoms. [1]
  3. DNA sequencing suggests monkeypox may have been circulating in people for years. [2]
  4. The pattern seen means that there has been sustained human to human transmission since at least 2017 and spreading quite widely in people in Africa. In some African countries person-to-person spread is likely to have gone unnoticed for years. [2]
  5. Genome sequencing shows that the monkeypox viruses responsible for these cases are closely related to ones detected in a small number of cases in Israel, Nigeria, Singapore and the UK between 2017 and 2019. [2]
  6. The 47 DNA-letter changes in the latest viruses compared with earlier ones is an unexpectedly high number of mutations. [2]
  7. We shouldn’t assume that monkeypox won’t evolve to be better at spreading in people if given a chance. [2]
  8. There is no reason to panic as this is something we can get under control. But we have to take it seriously. [2]
  9. Genetic testing identified two strains of monkeypox in the US. Most US cases involved the strain linked to the recent outbreak first identified in European countries. However the presence of a second variant suggests the virus may have been spreading unnoticed for some time. Data from many more patients will be needed to estimate how long the virus has been circulating in the US. [3]
  10. In England it is now a legal requirement for doctors to notify their local council or health protection team about any suspected monkeypox cases – as they have to for measles, scarlet fever and tuberculosis. [4]
  11. The UK Health Security Agency (UKHSA) has detected to 524 cases as of 14 June. [5]
  12. More than 1800 cases of monkeypox have now been confirmed in dozens of countries outside Africa in the latest outbreak. [6]
  13. The World Health Organization has said it will rename monkeypox to avoid discrimination and stigmatisation as the virus continues to spread. The working name is “hMPXV” for “human monkeypox virus”. [6]

References

[1] https://www.bbc.co.uk/news/health-61696974
[2] https://www.newscientist.com/article/2323019-monkeypox-dna-hints-virus-has-been-spreading-in-people-for-years/ [£££]
[3] https://www.the-scientist.com/news-opinion/monkeypox-likely-spread-undetected-in-us-before-recent-reports-70102
[4] https://www.bbc.co.uk/news/health-61723964
[5] https://www.gov.uk/government/news/monkeypox-cases-confirmed-in-england-latest-updates
[6] https://www.theguardian.com/world/2022/jun/15/who-to-rename-monkeypox-virus-to-avoid-discrimination


Ten Things: June

This year our Ten Things each month are words with particular endings. Clearly this won’t be all the words with the nominated ending, but a selection of the more interesting and/or unusual.

Ten Words ending with -i

  1. dhobi
  2. mehari
  3. punani
  4. barramundi
  5. maharishi
  6. origami
  7. chapati
  8. biryani
  9. kimchi
  10. yogini

Your challenge, if you choose to accept it, is to write a story in at most three sentences using all these words correctly. Post your attempt in the comments before the end of the month and there’s an e-drink for anyone who I consider succeeds.

Culinary Adventures #87. Long Jubilee Holiday Weekend

So that’s the end of a a long Jubilee holiday weekend (plus Monday) on which we did little except eat like the gentry (as I’m sure our great-great-grandfathers would say).


Thursday
All-in-One Duck, Fennel & Asparagus Salad with Croutons
Raspberries & Cream
Ionos Greek White Wine


Friday

Crab, Tomato & Mushroom about to meet its Pasta

Crab with Tomato, Mushroom and Spaghetti
Strawberries & Cream
Champagne; Domaine Tariquet “Le Légendaire” Armagnac


Saturday
Tangy Stir-fry Pork with Pepper, Asparagus & Noodles
Deconstructed Ealing Mess: Strawberries & Almond Croissant Pieces with Cream
Domaine Maby Tavel Rosé 2020


Sunday
All-in-One Chicken Tikka, Asparagus & Tomato Salad with Croutons
Large, long, gin & tonic


Monday
Thick Rump Steaks, Chips & Asparagus
Summer Pudding & Cream
Champagne; Armagnac (as above)


Main courses (except Sunday) done by me; puddings and Sunday main by N.

And now we return to sausage & mash, and fish finger sandwiches. ☺☺

Imperial Measurements Consultation

In a move typical of obfuscatory government everywhere, on Friday 3 June, a public holiday, the UK government slipped out a purported consultation on the suggestion of the UK reverting from metric to Imperial measurements.

I’m not going to rehearse the arguments here – I have better things to do, like cook dinner. However my polite response is basically: If it isn’t broken, don’t fix it.

The current system isn’t broken; it doesn’t need to be changed; although it could be improved by removing the last vestiges of Imperial measurements which remain.

You can find the consultation at https://www.gov.uk/government/consultations/choice-on-units-of-measurement-markings-and-sales. The consultation is open until 26 August (which you also aren’t told except hidden in the documentation).

Anyone may respond: so please do.

H/T Martin McKee, @martinmckee on Twitter.

Monkeypox 6. Quick Updates

This is really going to be just a quick few updates of some of the salient features I spotted in the last few days.

The headline message remains: The risk is low so don’t be concerned, but do be vigilent.


Illness & Precautions

  1. Infection during pregnancy can lead to miscarriage. [1]
  2. A child’s temperature is likely to be higher with monkeypox, and they may complain of backache, lower leg aches, chills, and very tender glands around their neck. The blisters are bigger with monkeypox (cf. chickenpox). [2]
  3. People with monkeypox have been told to avoid contact with their pets for three weeks amid concerns the animals could become infected and pass the virus on to other people. However the risk of someone passing monkeypox to their pet is low and no cases of monkeypox have ever been suspected or reported in pets in the UK. [3]
  4. People who have tested positive for the virus and their close contacts are being told to isolate at home for 21 days. They should avoid contact with other people until all lesions – or blisters – have healed and scabs have dried off. [4]
  5. Anyone testing positive is being told to abstain from sex while they have symptoms, and then use condoms for 8 weeks as a precaution. [4]
  6. Confirmed cases and their close contacts should take extra care if they need to leave the house to see a doctor or other health worker. [4]

Epidemiology

  1. Health officials are reporting that the current monkeypox outbreak is mostly affecting younger men in London. Although anyone can contract the virus, 111 of 183 cases** in England are in men who have sex with men. In England, 86% of those infected live in London and only two are women. Most are aged 20 to 49. [5]
    (** This was a couple of days ago and the numbers have increased since then. The UK government regularly publishes the latest figures etc. [11])
  2. People aged 50 and above are likely to be immune (they’re more likely to have had a smallpox vaccination) but the under-50s are more susceptible. [7]
  3. The recent outbreak of monkeypox is being linked to events taking place in Spain and Belgium, according to a leading advisor to the WHO. And the authorities are investigating possible links between a recent Gay Pride event in the Canary Islands, which drew 80,000 people, and cases at a Madrid sauna. [6]
  4. Experts in Africa have warned that monkeypox could change from a regionally widespread zoonosis to a globally relevant infectious disease. The virus may be filling the ecological and immunological niche once occupied by the smallpox virus now that smallpox vaccination has ceased. [1]
  5. Which means this was an outbreak waiting to happen after the end of global smallpox vaccination more than 40 years ago. [7]
  6. There’s unlikely to be the same “explosive growth” of infections into the general population that was witnessed with Covid. However the outbreak could continue for several months as contact tracing slows but does not stop transmission. [7]
  7. Scientists are working through how the disease came to flare up in so many countries in such a short space of time. Many suspect that monkeypox was circulating at low levels, undetected, in the UK or Europe for several years before it reached the MSM community and flared up. [8]
  8. Genetic studies on monkeypox viruses taken from people in the ongoing outbreak show a close resemblance to the virus that reached the UK, Israel and Singapore from Africa in 2018 and 2019. They all have a common ancestor which probably dates back to 2019. [8]
  9. Data from the Democratic Republic of the Congo in the early-1980s and mid-2010s suggest the effective reproduction numbers at those times were 0.3 and 0.6, respectively – meaning each infected person passed the virus to fewer than one person in those populations, on average. [1]
  10. DNA viruses like these are a lot larger and more complicated than RNA viruses like Coronaviruses. Coronaviruses are among the largest RNA viruses known, at about 30,000 base pairs, but things like monkeypox are up over 200,000 bp. [9]

Zoonotic Concerns

  1. The infection can be spread by animals, and pet owners have been urged to “manage exposed pets and prevent the disease from being transmitted to wildlife”. [10]
  2. The EU has warned that the zoonotic transfer to humans could spill over yet again from humans to other mammals, potentially making monkeypox endemic in Europe. That’s a real concern, since we know the disease can be carried by a variety of small mammals. But what we don’t know is the likelihood of humans passing it on to animals, or the disease getting established among those animal populations in the wild. [9]
  3. Some of our most troublesome infectious disease threats – think Ebola, or Nipah, or coronaviruses, and now monkeypox – are disproportionately zoonotic diseases. [1]

References

[1] https://www.scientificamerican.com/article/what-we-know-about-the-rise-in-monkeypox-cases-worldwide/ [£££]
[2] https://www.thisislocallondon.co.uk/news/national/uk-today/20163472.uk-monkeypox-outbreak-tell-difference-chickenpox-monkeypox/
[3] https://www.theguardian.com/science/2022/may/27/monkeypox-patients-contact-pets-uk
[4] https://www.bbc.co.uk/news/health-61640196
[5] https://www.bbc.co.uk/news/health-61660180
[6] https://www.thisislocallondon.co.uk/news/national/uk-today/20160206.monkeypox-outbreak-sex-raves-spain-belgium-may-blame/
[7] https://www.theguardian.com/world/2022/may/24/monkeypox-outbreak-was-waiting-to-happen-say-scientists
[8] https://www.theguardian.com/world/2022/may/25/monkeypox-may-have-been-circulating-in-uk-for-years-scientists-say
[9] https://www.science.org/content/blog-post/now-monkeypox
[10] https://www.thisislocallondon.co.uk/news/national/uk-today/20162530.monkeypox-pet-owners-urged-manage-exposed-pets-uk-cases-rise/
[11] https://www.gov.uk/government/news/monkeypox-cases-confirmed-in-england-latest-updates

June Quiz Questions

This year we’re beginning each month with five pub quiz style questions, with a different subject each month. They’re not difficult, but it is unlikely everyone will know all the answers, so hopefully you’ll learn something new, as well as have a bit of fun.

June Quiz Questions: Famous Quotations

Who said …

  1. “Any sufficiently advanced technology is indistinguishable from magic.”
  2. “Every harlot was a virgin once.”
  3. “I have always believed that I was slightly saner than most people. Then again, most insane people think this.”
  4. “For a successful technology, reality must take precedence over public relations, for nature cannot be fooled.”
  5. “In converting Jews to Christians, you raise the price of pork.”

Answers will be posted in 3 weeks time.