One person outside but two people inside. That’s the gist of the chimera, a human being who carries the DNA (and sometimes the body parts) for two. It sounds crazy, but it happens. In fact, doctors think it probably happens more often than we realize. Unless there were some reason to test the DNA from cells in different parts of your body, you could easily be a chimera and never know it.
A chimera is a single organism composed of genetically distinct cells. This can result in male and female organs, two different blood types, or subtle variations in form. Animal chimeras are produced by the merger of multiple fertilized eggs.
Tetragametic chimerism occurs through the fertilization of two separate ova by two sperm, followed by aggregation of the two at the blastocyst or zygote stages. This results in the development of an organism with intermingled cell lines. Put another way, the chimera is formed from the merging of two non-identical twins. As such, they can be male, female, or have mixed intersex characteristics.
This can produce an organism with totally different characteristics on each side of the body: different genders or different colouring — as in the budgie above. Or it can cause mozaicism where the organism contains patches of the different cell types, something most easily spotted in coat colouring — as in the human above — or eye colour.
But very often the mosaicism is there; we just don’t know it.

Haemoglobin is best known as red blood cells’ superstar protein — carrying oxygen and other gases on the erythrocytes as they zip throughout the bodies of nearly all vertebrates. Less well known is its presence in vegetables, including the sugar beet … In fact, many land plants — from barley to tomatoes — contain the protein … Scientists first discovered them in the bright-red nodules of soybean roots in 1939 but have yet to determine the proteins’ role in plants in most cases … Plant haemoglobins might … serve as a blood substitute for humans someday … Or they could be exploited to trick our senses … as an ingredient in veggie burgers to make them taste more like bloody steaks.





Alice Roberts is Professor of Public Engagement with Science at the University of Birmingham, and is perhaps the outstanding scientific polymath of our age: medic, anatomist, anthropologist, archaeologist, television science presenter and no mean artist. The Incredible Unlikeliness of Being is her latest book and sets out to unfold for us the amazing way in which we develop as an embryo and foetus and some of the ways in which we have probably evolved to this. And what an amazing voyage we are taken on!