I rather like this XKCD from earlier in the week:

Click the image for a larger view
I rather like this XKCD from earlier in the week:

Penelope A Lewis
The Secret World of Sleep: The Surprising Science of the Mind at Rest
Palgrave Macmillan, 2013
This is another of those books which I wanted to read and which appeared for either Christmas or my birthday (I forget now which as they are quite close together). This is what the cover blurb says:
A highly regarded neuroscientist explains the little-known role of sleep in processing our waking life and making sense of difficult emotions and experiences.
In recent years neuroscientists have uncovered the countless ways our brain trips us up in day-to-day life, from its propensity toward irrational thought to how our intuitions deceive us. The latest research on sleep, however, points in the opposite direction. Where old wives’ tales have long advised to “sleep on a problem,” today scientists are discovering the truth behind these folk sayings and how the busy brain radically improves our minds through sleep and dreams. In The Secret World of Sleep, neuroscientist Penny Lewis explores the latest research into the nighttime brain to understand the real benefits of sleep. She shows how, while our body rests, our brain practices tasks it learned during the day, replays traumatic events to mollify them, and forges connections between distant concepts. By understanding the roles that the nocturnal brain plays in our waking life, we can improve the relationship between the two and even boost creativity and memory. This is a fascinating exploration of one of the most surprising corners of neuroscience that shows how science may be able to harness the power of sleep to improve learning, health, and more.
Yes, OK, I guess it does do all of that and at a level which is likely OK for the intelligent layman. But as a scientist I found it somewhat lacking, or maybe more correctly it felt loose, in the details. I don’t profess to be very knowledgeable about the neurology of sleep, but I had the feeling that there was more there which is known and which would tie everything together. I may be wrong, and in fairness to Lewis she does say at a number of points “we don’t know how this works”.
Did it tell me anything I didn’t know? Well nothing which I found helpful and which has stuck sufficiently that I could recite it now. As always, yes, OK, I’m probably way above the audience this was written for. I found it an easy but not compelling, or gripping, read — sufficiently so that I whizzed through it far faster than I had expected.
All of this is a shame because I wanted to get that “Wow!” inspirational insight and it didn’t happen. I still feel it should.
As with many modern books it is a slim volume (about 190 pages) and it could have been much slimmer: as always there is too much white space on the page. Even if you don’t want to reduce the font size the leading could certainly be reduced, as could the margins slightly. That would make it a more compact volume, both in looks and physically.
I was also not struck on the cartoon-style illustrations. I didn’t find them illuminating (indeed at times downright confusing) and felt that maybe a few more, better, diagrams were needed for the target audience.
One thing which Lewis does however do well is to write a summary paragraph or two at the end of each chapter. Other authors please copy.
Is this a bad book? No, certainly not. It would likely work very well for an intelligent layman. It is merely that it didn’t work for me; but then it probably wasn’t intended to.
Overall Rating: ★★★☆☆
Orchidectomy
The excision of one or both of the testicles; castration.
This is derived from the Greek ὄρχις (orkhis, a testicle) + ἐκτοµή (ektomi, cutting-out).
According to the OED the first recorded usage was in 1870.
We are exposed to ionising radiation every minute of every day, much of it in the form of background radiation including cosmic rays, rocks in the ground, radon gas, water and food.

Interesting events and anniversaries in the coming month.
1 February
Start of the last London Frost Fair, 1814 which lasted four days, during which time an elephant was led across the river below Blackfriars Bridge. This was the last frost fair because the climate was growing milder; old London Bridge was demolished in 1831 and replaced with a new bridge with wider arches, allowing the tide to flow more freely; and the river was embanked in stages during the 19th century, all of which made it less likely to freeze.


This week’s photograph was taken last summer while sitting outside a pub in London’s Covent Garden. The guy spend quite some minutes ferreting around his pockets while making mobile phone calls, it appeared all in aid of paying for parking his motorbike. It was street performance at it’s best — completely impromptu!

So according to all yesterday’s media — see for example the Guardian and the BBC — we patients need to be much more pushy with our GPs to get the best drugs.

When products have been approved for use by the NHS by Nice, patients have a legal right to those drugs — as long as they are clinically appropriate. The take-up should be much higher than it currently is.
Patients have a right under the NHS constitution to these therapies, so I really hope we can improve this.
The fundamental point is, it’s your body.
And the more you understand about the drugs you are taking, or what you might be able to have, the better you are able to work with your doctor.
Several things strike me about this.
Firstly, I cannot disagree with Prof. Haslam’s sentiments. There are drugs which people aren’t getting, for all sorts of reasons including the so-called “postcode lottery” of care provision.
And I applaud his stance that we take responsibility for our bodies, understand them and how they work. This has to be good — as regular readers will know I am a vocal advocate of being comfortable with, and talking about your body, as a route to improved medical care.
But there are several things which worry me here.
We have to be realistic and accept that, sadly, many people are not able to understand even the rudiments of how human physiology works and how drugs work. Unfortunately these are mostly the very people who are going to latch onto some drug/treatment they think they should have and be abusive with their GP when they aren’t given it. Doctors are already under enough pressure, and get enough abuse from patients, that they don’t need more.
And then there are the people who really don’t want to think about these things and want to just trust their doctor to give them the best treatment. Not everyone, regardless of intellectual capability, wants to be engaged in the way Prof. Haslam would like. Yes there is still too much of the doctor as demigod who knows best, but there will always be those who treat any professional this way.
Finally I worry about who will pay for all this. I wouldn’t mind betting that many of the drugs we should be demanding are more expensive than the ones we are being prescribed now. So Prof. Haslam’s approach is going to see the NHS drugs bill increase, perhaps dramatically. You watch in a year or so the NHS will be squealing because the drugs budget is out of control.
But perhaps the biggest problem is how we patients actually find out about which drugs are best for us. I reckon I’m pretty good at ferreting out information and have research skills, but even I find it hard to sort the wheat from the chaff when it comes to drugs — especially when so much drug trial data has never been published.
Another catch-up on items you may have missed.
Let’s get the most serious one out of the way first. Here’s a collection of snippets and links to all the best, scientifically verified, information on the impacts of the Fukushima disaster. And of course when looked at objectively it isn’t half so bad as most make out.
So what does happen when water freezes in a box so strong it can’t expand? Can you even do this?
Here’s a story about a tube train, some concrete and some sugar. Or how sugar helped remove concrete which had flooded a Victoria Line control room. I never cease to be surprised by the weirdness that is concrete.
So here you go with my answer to question three of the Five Questions in Series 5 that I posed at the beginning of the month.
