Entheogen
A psychoactive substance which is used in a religious or shamanic ritual or to bring about a spiritual experience, typically a plant or fungal extract.
Entheogens can supplement many diverse practices for transcendence and revelation, including meditation, psychedelic art and magic.

Entheogens have been used in a ritualized context for thousands of years; their religious significance is well established in anthropological and ethnographic studies. Examples of traditional entheogens include: peyote, psilocybin mushrooms, cannabis, ayahuasca and Amanita muscaria.
The OED says the word was first used in 1979 and is derived from the ancient Greek ἔνθεος, divinely inspired, or perhaps more literally “creating god within”.